The town stands 45 m. above sea level on fertile plains near the left bank of the Po River, just past its confluence with the Adda River.
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Of Gallic origin, it became a Roman colony (218 BC.). After the fall of the Empire, it was subject to Barbarian invasions before becoming a free municipality in the 11th century, often at war with the other Lombard towns; it fell to Visconti rule in the 14th century.
After that for brief intervals, Cremona formed part of the Duchy of Milan, sharing its destiny, and after the Lombard-Venetia period, it was involved in the Italian Risorgimento.